An Update on the Vaccinia Virus Genome

This communication is intended as a single source update of the initial report (Goebel et al., 1990a,b) which described the complete DNA sequence of the vaccinia virus genome. We have integrated published information as well as unpublished data. Our understanding of the complexities of the genetic f...

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Veröffentlicht in:Virology 1993-10, Vol.196 (2), p.381-401
Hauptverfasser: Johnson, Gerard P., Goebel, Scott J., Paoletti, Enzo
Format: Artikel
Sprache:eng
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Zusammenfassung:This communication is intended as a single source update of the initial report (Goebel et al., 1990a,b) which described the complete DNA sequence of the vaccinia virus genome. We have integrated published information as well as unpublished data. Our understanding of the complexities of the genetic functional organization of poxviruses is increasing at a remarkable rate. While some previously unknown identities have since been elucidated, the fact that the majority of vaccinia-encoded gene products still lack assigned functions lends excitement to the immediate future of poxvirus research.
ISSN:0042-6822
1096-0341
DOI:10.1006/viro.1993.1494