Monoxycarbogenic reaction of chloral: application to the obtention of carboxyhemoglobin and to its determination in blood

Monoxycarbogenic reaction of chloral: application to the obtention of carboxyhemoglobin and to its determination in blood

Carbon monoxide CO, generated from chloral (10(-2) M) in a dilution of hemochrome (pH 13), turns the solution of hemochrome into a solution of carboxyhemoglobin. The spectrum of this solution is identical to the one obtained after bubbling with CO. The reaction is fast and makes it possible to deter...

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Veröffentlicht in:Comptes rendus de l'Académie des sciences, Série III, Sciences de la vie Série III, Sciences de la vie, 1993, Vol.316 (3), p.163-168
Hauptverfasser: Malbosc, R, Broqua, C, Tufenkji, A E, Bergeal, M F, Mabon, N
Format: Artikel
Sprache:fre
Schlagworte:
Carbon Monoxide - chemical synthesis
Carboxyhemoglobin - pharmacokinetics
Chloral Hydrate - analogs & derivatives
Chloral Hydrate - pharmacology
Spectrophotometry - methods
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Zusammenfassung:Carbon monoxide CO, generated from chloral (10(-2) M) in a dilution of hemochrome (pH 13), turns the solution of hemochrome into a solution of carboxyhemoglobin. The spectrum of this solution is identical to the one obtained after bubbling with CO. The reaction is fast and makes it possible to determine the percentage of carboxyhemoglobinemia in whole blood.
ISSN:0764-4469