Hydrolytic Enzyme Production is Associated with Candida Albicans Biofilm Formation from Patients with Type 1 Diabetes

Oral candidosis is common in patients with diabetes mellitus, as yeasts, particularly Candida albicans, have the propensity to colonise, form biofilms and release hydrolytic enzymes which cause inflammation. This study aimed to investigate these characteristics in isolates from three groups of patie...

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Veröffentlicht in:	Mycopathologia (1975) 2010-10, Vol.170 (4), p.229-235
Hauptverfasser:	Rajendran, Ranjith, Robertson, Douglas P, Hodge, Penny J, Lappin, David F, Ramage, Gordon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult biofilm Biofilms - growth & development Biomedical and Life Sciences Candida Candida albicans Candida albicans - enzymology Candida albicans - physiology Candidiasis, Oral - microbiology Diabetes Mellitus, Type 1 - complications Diabetes therapy Diabetics Eukaryotic Microbiology Female Fungal Proteins - biosynthesis Haemolysin Hemolysin Proteins - biosynthesis Humans Life Sciences Male Medical Microbiology Microbial Ecology Microbiology Middle Aged Nucleotidases Peptide Hydrolases - biosynthesis Phospholipase Phospholipases Phospholipases - biosynthesis Physiological aspects Plant Sciences Proteinase Type 1 diabetes Type 1 diabetes mellitus
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Zusammenfassung:	Oral candidosis is common in patients with diabetes mellitus, as yeasts, particularly Candida albicans, have the propensity to colonise, form biofilms and release hydrolytic enzymes which cause inflammation. This study aimed to investigate these characteristics in isolates from three groups of patients with type 1 diabetes: individuals with better controlled diabetes (BCD; ≥6
ISSN:	0301-486X 1573-0832
DOI:	10.1007/s11046-010-9319-0