Diuretics and calcium metabolism

In this review the normal renal tubular handling of calcium is briefly described. A detailed examination follows of the sites and modes of action of furosemide and thiazide diuretics on renal calcium handling and overall calcium metabolism. The clinical applications of these effects are also conside...

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Veröffentlicht in:	American journal of kidney diseases 1985-01, Vol.5 (1), p.4-9
1. Verfasser:	Sutton, R A
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Acetazolamide - pharmacology Adult Animals Benzothiadiazines Calcium - blood Calcium - metabolism Calcium - urine Diuretics Dogs Furosemide - pharmacology Humans Kidney Calculi - drug therapy Kidney Tubules - metabolism Loop of Henle - metabolism Sodium Chloride Symporter Inhibitors - pharmacology Sodium Chloride Symporter Inhibitors - therapeutic use
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Beschreibung
Zusammenfassung:	In this review the normal renal tubular handling of calcium is briefly described. A detailed examination follows of the sites and modes of action of furosemide and thiazide diuretics on renal calcium handling and overall calcium metabolism. The clinical applications of these effects are also considered. Finally, the use of diuretics with different tubular sites of action on calcium transport as probes to study disorders of calcium excretion is discussed.
ISSN:	0272-6386
DOI:	10.1016/S0272-6386(85)80128-1