Fetal organs infected by HIV-1

The transmission rate of HIV from mother to fetus via the placenta is estimated to be 12-50% (1-3). Because differences in fetal outcome may be influenced by time of viral transmission in utero and type of infected fetal cell, we examined 28 embryos/fetuses (10-27th week of gestation) by polymerase...

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Veröffentlicht in:AIDS (London) 1993-06, Vol.7 (6), p.896-897
Hauptverfasser: Backé, E, Unger, M, Jimenez, E, Siegel, G, Schäfer, A, Vogel, M
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container_title AIDS (London)
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creator Backé, E
Unger, M
Jimenez, E
Siegel, G
Schäfer, A
Vogel, M
description The transmission rate of HIV from mother to fetus via the placenta is estimated to be 12-50% (1-3). Because differences in fetal outcome may be influenced by time of viral transmission in utero and type of infected fetal cell, we examined 28 embryos/fetuses (10-27th week of gestation) by polymerase chain reaction (PCR), RNA in situ hybridization and immunostaining (not all cases were investigated by all three methods).
doi_str_mv 10.1097/00002030-199306000-00025
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subjects Adult
AIDS/HIV
DNA, Viral - analysis
Female
Fetus - microbiology
Gestational Age
HIV - isolation & purification
HIV Infections - embryology
HIV Infections - microbiology
HIV Infections - transmission
human immunodeficiency virus 1
Humans
In Situ Hybridization
Lymphoid Tissue - embryology
Lymphoid Tissue - microbiology
Maternal-Fetal Exchange
Organ Specificity
Placenta - microbiology
Placenta - physiology
Polymerase Chain Reaction
Pregnancy
Pregnancy Complications, Infectious
Proviruses - isolation & purification
RNA, Viral - analysis
Viscera - embryology
Viscera - microbiology
title Fetal organs infected by HIV-1
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