Portable system for continuous ex vivo measurements of lactate

The lactate profile in serum was monitored continuously in volunteers under physical exercise on a test bicycle. The assay was operated ex vivo by means of continuous sampling through a coaxial catheter. After dialysis online, lactate was converted by means of lactate oxidase immobilized to porous g...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biosensors & bioelectronics 1993, Vol.8 (3), p.213-217
Hauptverfasser:	Håkanson, Håkan, Kyröläinen, Marika, Mattiasson, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of complex biological substances Analytical, structural and metabolic biochemistry Biological and medical sciences Biosensing Techniques biosensor Biotechnology Blood and biological fluids Catalase - metabolism continuous monitoring enzyme ex-vivo Exercise Fundamental and applied biological sciences. Psychology Humans lactate Lactates - blood Mixed Function Oxygenases - metabolism Monitoring, Physiologic - methods Physical Exertion
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The lactate profile in serum was monitored continuously in volunteers under physical exercise on a test bicycle. The assay was operated ex vivo by means of continuous sampling through a coaxial catheter. After dialysis online, lactate was converted by means of lactate oxidase immobilized to porous glass, and the depletion of oxygen was registered by means of a Clark electrode. Good agreement between the continuous monitoring and off-line analyses was found.
ISSN:	0956-5663 1873-4235
DOI:	10.1016/0956-5663(93)85036-N