Plasmid-borne streptothricin resistance in gram-negative bacteria

Plasmid-borne streptothricin resistance in gram-negative bacteria

Plasmids, which code for a new type of drug resistance due to the acetylation of streptothricin and belonging to various incompatibility groups (I1, I2, W3, FII, S, X, and N) were identified in gram-negative bacteria. The gene for the acetyltransferase is closely linked to a gene for the streptomyci...

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Veröffentlicht in:Plasmid 1984-01, Vol.12 (3), p.189-196
Hauptverfasser: Tschäpe, H., Tietze, E., Prager, Rita, Voigt, W., Wolter, E., Seltmann, G.
Format: Artikel
Sprache:eng
Schlagworte:
Acetyltransferases - genetics
Anti-Bacterial Agents - pharmacology
Bacteriology
Biological and medical sciences
DNA Transposable Elements
Drug Resistance, Microbial
Escherichia coli - drug effects
Escherichia coli - enzymology
Escherichia coli - genetics
Fundamental and applied biological sciences. Psychology
Genes, Bacterial
Genetics
Microbiology
Nucleotidyltransferases - genetics
R Factors
Streptothricins - pharmacology
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Zusammenfassung:Plasmids, which code for a new type of drug resistance due to the acetylation of streptothricin and belonging to various incompatibility groups (I1, I2, W3, FII, S, X, and N) were identified in gram-negative bacteria. The gene for the acetyltransferase is closely linked to a gene for the streptomycin/spectinomycin adenylyltransferase AAD-3″ on a novel type of a transposon, designated Tn1825. This is related to Tn7.
ISSN:0147-619X
1095-9890
DOI:10.1016/0147-619X(84)90043-X