Development of fiber types in human fetal muscle: An immunocytochemical study

Human fetal muscles have been studied using immunocytochemical methods with antibodies directed against different myosin isoforms. We show that fiber type differences can be detected as early as 15–16 weeks of gestation. At this time it would appear that both the heavy and light chains characteristi...

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Veröffentlicht in:	Journal of the neurological sciences 1984-01, Vol.66 (1), p.107-115
Hauptverfasser:	Thornell, Lars-Eric, Billeter, Rudi, Butler-Browne, Gillian S., Eriksson, Per-Olof, Ringqvist, Margareta, Whalen, Robert G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Biological and medical sciences Embryology: invertebrates and vertebrates. Teratology Fiber types fibers Fundamental and applied biological sciences. Psychology Human fetal muscle Humans Immunocytochemistry Immunoenzyme Techniques man muscles Muscles - cytology Muscles - embryology Muscles - metabolism myosin Myosin isoforms Myosins - metabolism Organogenesis. Fetal development Organogenesis. Physiological fonctions
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Zusammenfassung:	Human fetal muscles have been studied using immunocytochemical methods with antibodies directed against different myosin isoforms. We show that fiber type differences can be detected as early as 15–16 weeks of gestation. At this time it would appear that both the heavy and light chains characteristic of slow myosin are found in some myotubes.
ISSN:	0022-510X 1878-5883
DOI:	10.1016/0022-510X(84)90146-1