Selective inhibition of mammalian lanosterol 14α-demethylase : a possible strategy for cholesterol lowering

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Veröffentlicht in:	Journal of medicinal chemistry 1993-07, Vol.36 (15), p.2235-2237
Hauptverfasser:	WALKER, K. A. M, KERTESZ, D. J, MILLS-DUNLAP, B, CHIOU, M. Y, TOKES, L. G, KURZ, L. J, KERN, J. R, CHAN, K. W, AMID SALARI, MENDIZABAL, G. R, ROTSTEIN, D. M, SWINNEY, D. C, BERRY, P. W, ON-YEE SO, WEBB, A. S, WATSON, D. M, MAK, A. Y, BURTON, P. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aniline Compounds - chemical synthesis Aniline Compounds - pharmacology Animals Anticholesteremic Agents - chemical synthesis Anticholesteremic Agents - pharmacology Chemistry Cholesterol - blood Cricetinae Cytochrome P-450 Enzyme Inhibitors Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - pharmacology Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms Humans Organic chemistry Oxidoreductases - antagonists & inhibitors Preparations and properties Rats Stereoisomerism Sterol 14-Demethylase Structure-Activity Relationship Sulfides - chemical synthesis Sulfides - pharmacology
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