Localization of Met5-enkephalin-Arg6-Phe7-like immunoreactivity in the rat gastrointestinal tract
The distribution of Met5-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe)-like immunoreactivity in the rat gastrointestinal tract was studied by immunohistochemical techniques. Antiserum against a Met-Enk-Arg-Phe-thyroglobulin conjugate was raised in rabbits and was found to be specific for synthetic Met-Enk-...
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| Veröffentlicht in: | Neuroscience letters 1984-10, Vol.51 (3), p.319-324 |
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| container_title | Neuroscience letters |
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| creator | YEN-NUNG WANG CHURCH, A. C WYATT, R. J |
| description | The distribution of Met5-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe)-like immunoreactivity in the rat gastrointestinal tract was studied by immunohistochemical techniques. Antiserum against a Met-Enk-Arg-Phe-thyroglobulin conjugate was raised in rabbits and was found to be specific for synthetic Met-Enk-Arg-Phe. Met-Enk-Arg-Phe-like immunoreactivity was found in neuronal structures in all parts of the rat gastrointestinal tract. Immunostained somata were primarily located in myenteric plexus; immunostained processes were mostly present in myenteric plexus and circular muscle layer. This distribution pattern is similar to that of the three other opioid polypeptides, Met5-enkephalin, Leu5-enkephalin and Met5-enkephalin-Arg6-Gly7-Leu8. |
| doi_str_mv | 10.1016/0304-3940(84)90396-3 |
| format | Article |
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This distribution pattern is similar to that of the three other opioid polypeptides, Met5-enkephalin, Leu5-enkephalin and Met5-enkephalin-Arg6-Gly7-Leu8.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/0304-3940(84)90396-3</identifier><identifier>PMID: 6395044</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier</publisher><subject>Animals ; Biological and medical sciences ; Digestive System - metabolism ; Enkephalin, Methionine - analogs & derivatives ; Enkephalin, Methionine - metabolism ; Female ; Fluorescent Antibody Technique ; Fundamental and applied biological sciences. 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C</creatorcontrib><creatorcontrib>WYATT, R. J</creatorcontrib><title>Localization of Met5-enkephalin-Arg6-Phe7-like immunoreactivity in the rat gastrointestinal tract</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>The distribution of Met5-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe)-like immunoreactivity in the rat gastrointestinal tract was studied by immunohistochemical techniques. Antiserum against a Met-Enk-Arg-Phe-thyroglobulin conjugate was raised in rabbits and was found to be specific for synthetic Met-Enk-Arg-Phe. Met-Enk-Arg-Phe-like immunoreactivity was found in neuronal structures in all parts of the rat gastrointestinal tract. Immunostained somata were primarily located in myenteric plexus; immunostained processes were mostly present in myenteric plexus and circular muscle layer. This distribution pattern is similar to that of the three other opioid polypeptides, Met5-enkephalin, Leu5-enkephalin and Met5-enkephalin-Arg6-Gly7-Leu8.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Digestive System - metabolism</subject><subject>Enkephalin, Methionine - analogs & derivatives</subject><subject>Enkephalin, Methionine - metabolism</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Male</subject><subject>Myenteric Plexus - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Submucous Plexus - metabolism</subject><subject>Vertebrates: digestive system</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtKxDAUhoMoOl7eQKELEV1Ec22a5SDeYEQXug6naepE23RMMoI-vR0dZnXgnO__OXwIHVNySQktrwgnAnMtyHklLjThusR8C01opRhWWrFtNNkge2g_pXdCiKRS7KLdkmtJhJggmA0WOv8D2Q-hGNri0WWJXfhwi_m4D3ga30r8PHcKd_7DFb7vl2GIDmz2Xz5_Fz4Uee6KCLl4g5Tj4EN2KfsAXZHjiB2inRa65I7W8wC93t68XN_j2dPdw_V0hi0recalAF1XtiZSg9WWSCFs01ghRasbBjWvtC2Jo1QJCrq0DhrGXc2gtYopkPwAnf33LuLwuRxfML1P1nUdBDcsk1GykooJPoLiH7RxSCm61iyi7yF-G0rMyqxZaTMrbaYS5s-sWcVO1v3LunfNJrRWOd5P13dIo9I2QrA-bbBKK8Kk5r-ai4ID</recordid><startdate>19841026</startdate><enddate>19841026</enddate><creator>YEN-NUNG WANG</creator><creator>CHURCH, A. 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J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c263t-64a9b8cb059ac9c0544cddc454f9d2ab389c60e11741a96cead23eb2afc727a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Digestive System - metabolism</topic><topic>Enkephalin, Methionine - analogs & derivatives</topic><topic>Enkephalin, Methionine - metabolism</topic><topic>Female</topic><topic>Fluorescent Antibody Technique</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Male</topic><topic>Myenteric Plexus - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Submucous Plexus - metabolism</topic><topic>Vertebrates: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>YEN-NUNG WANG</creatorcontrib><creatorcontrib>CHURCH, A. C</creatorcontrib><creatorcontrib>WYATT, R. J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>YEN-NUNG WANG</au><au>CHURCH, A. C</au><au>WYATT, R. J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Localization of Met5-enkephalin-Arg6-Phe7-like immunoreactivity in the rat gastrointestinal tract</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1984-10-26</date><risdate>1984</risdate><volume>51</volume><issue>3</issue><spage>319</spage><epage>324</epage><pages>319-324</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>The distribution of Met5-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe)-like immunoreactivity in the rat gastrointestinal tract was studied by immunohistochemical techniques. Antiserum against a Met-Enk-Arg-Phe-thyroglobulin conjugate was raised in rabbits and was found to be specific for synthetic Met-Enk-Arg-Phe. Met-Enk-Arg-Phe-like immunoreactivity was found in neuronal structures in all parts of the rat gastrointestinal tract. Immunostained somata were primarily located in myenteric plexus; immunostained processes were mostly present in myenteric plexus and circular muscle layer. This distribution pattern is similar to that of the three other opioid polypeptides, Met5-enkephalin, Leu5-enkephalin and Met5-enkephalin-Arg6-Gly7-Leu8.</abstract><cop>Shannon</cop><pub>Elsevier</pub><pmid>6395044</pmid><doi>10.1016/0304-3940(84)90396-3</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 1984-10, Vol.51 (3), p.319-324 |
| issn | 0304-3940 1872-7972 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Biological and medical sciences Digestive System - metabolism Enkephalin, Methionine - analogs & derivatives Enkephalin, Methionine - metabolism Female Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology General aspects Male Myenteric Plexus - metabolism Rats Rats, Inbred Strains Submucous Plexus - metabolism Vertebrates: digestive system |
| title | Localization of Met5-enkephalin-Arg6-Phe7-like immunoreactivity in the rat gastrointestinal tract |
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