Localization of Met5-enkephalin-Arg6-Phe7-like immunoreactivity in the rat gastrointestinal tract

The distribution of Met5-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe)-like immunoreactivity in the rat gastrointestinal tract was studied by immunohistochemical techniques. Antiserum against a Met-Enk-Arg-Phe-thyroglobulin conjugate was raised in rabbits and was found to be specific for synthetic Met-Enk-...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1984-10, Vol.51 (3), p.319-324
Hauptverfasser:	YEN-NUNG WANG, CHURCH, A. C, WYATT, R. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Digestive System - metabolism Enkephalin, Methionine - analogs & derivatives Enkephalin, Methionine - metabolism Female Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology General aspects Male Myenteric Plexus - metabolism Rats Rats, Inbred Strains Submucous Plexus - metabolism Vertebrates: digestive system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The distribution of Met5-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe)-like immunoreactivity in the rat gastrointestinal tract was studied by immunohistochemical techniques. Antiserum against a Met-Enk-Arg-Phe-thyroglobulin conjugate was raised in rabbits and was found to be specific for synthetic Met-Enk-Arg-Phe. Met-Enk-Arg-Phe-like immunoreactivity was found in neuronal structures in all parts of the rat gastrointestinal tract. Immunostained somata were primarily located in myenteric plexus; immunostained processes were mostly present in myenteric plexus and circular muscle layer. This distribution pattern is similar to that of the three other opioid polypeptides, Met5-enkephalin, Leu5-enkephalin and Met5-enkephalin-Arg6-Gly7-Leu8.
ISSN:	0304-3940 1872-7972
DOI:	10.1016/0304-3940(84)90396-3