Computer aided evaluation of two-dimensional NMR spectra of proteins

A computer program for the automatic evaluation of two-dimensional NMR spectra of peptides and proteins has been developped. The used strategy is described, the advantages and limits of this approach are discussed. The program was successfully tested on a COSY-spectrum of the neuropeptide Glp-Pro-Pr...

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Veröffentlicht in:	Biochemical and biophysical research communications 1984-12, Vol.125 (3), p.1143-1150
Hauptverfasser:	Neidig, K.P., Bodenmueller, H., Kalbitzer, H.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Applied sciences computer programs Computers Exact sciences and technology Hydra - analysis Magnetic Resonance Spectroscopy N.M.R Nerve Tissue Proteins - analysis Other techniques and industries Proteins Software
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Beschreibung
Zusammenfassung:	A computer program for the automatic evaluation of two-dimensional NMR spectra of peptides and proteins has been developped. The used strategy is described, the advantages and limits of this approach are discussed. The program was successfully tested on a COSY-spectrum of the neuropeptide Glp-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe from hydra, resulting in a drastic reduction of the time needed for the evaluation of two-dimensional NMR data.
ISSN:	0006-291X 1090-2104
DOI:	10.1016/0006-291X(84)91403-7