Histologic Determination of the Ischemic Threshold of Muscle in the Canine Compartment Syndrome Model

Our objective was to define the critical tissue pressure at which irreversible muscle damage occurs and to compare our results to those thresholds advocated in the orthopaedic literature. A standard plasma infusion compartment syndrome model was created in a canine model. Four dogs were in each of four experimental groups with compartment pressure maintained as follows(a) 30 mm Hg with support of diastolic blood pressure to a level