Altered in vitro uptake of norepinephrine by cardiovascular tissues of young spontaneously hypertensive rats

The authors investigated ( super(3)H)NE uptake by mesenteric artery and atria of SHR and their age-matched WKY at 3 and 4 weeks of age. The present study, represents the total ( super(3)H)NE uptake by the synaptosomal fraction including uptake of NE both from synaptic cleft to neuronal cytoplasm and...

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Veröffentlicht in:	Biochemical pharmacology 1984-12, Vol.33 (23), p.3906-3909
Hauptverfasser:	Rho, Joon H., Alexander, Natalie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Biological and medical sciences blood vessels Cardiology. Vascular system Heart Heart Atria - growth & development Heart Atria - metabolism hypertension Male Medical sciences Mesenteric Arteries - growth & development Mesenteric Arteries - metabolism Myocardium - metabolism norepinephrine Norepinephrine - metabolism Rats Rats, Inbred SHR Rats, Inbred WKY Subcellular Fractions - metabolism Synaptosomes - metabolism
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Zusammenfassung:	The authors investigated ( super(3)H)NE uptake by mesenteric artery and atria of SHR and their age-matched WKY at 3 and 4 weeks of age. The present study, represents the total ( super(3)H)NE uptake by the synaptosomal fraction including uptake of NE both from synaptic cleft to neuronal cytoplasm and from cytoplasm to the interior of storage vesicles.
ISSN:	0006-2952 1873-2968
DOI:	10.1016/0006-2952(84)90060-1