Obstetric performance of patients after oocyte donation

Objective: The purpose of this study was to evaluate the obstetric performance of patients after oocyte donation. Study Design: A review of five patients in the author's private practice who underwent successful donation with conception and a literature review specific to obstetric outcome were undertaken. Results: All five patients were delivered of healthy infants; however, significant maternal complications occurred, particularly in two patients with twin gestations. A literature review substantiates increased incidence of (1) multiple gestation, (2) pregnancy-induced hypertension, (3) placenta previa, (4) preterm labor, and (5) cesarean birth. Infant outcomes, however, were good. Conclusions: Women with premature ovarian failure and women over 40 years old can successfully conceive with oocyte and preembryo donation and successfully deliver healthy infants. More attention needs to be directed at maternal performance, particularly in those women over 40 years old. (Ann J OBSTET GVNECOL 1993;168:1803-9.)