Immunohistochemical localization of cathepsins B and D in the synovial lining cells of the normal rat temporomandibular joint

In 1 μm-thick serial cryosections, cathepsins B and D were found to coexist in both type A (macrophage-like) and type B (fibroblast-like) cells: the whole cytoplasm of the type A cells showed strong immunoreactivity, while the type B cells contained a few granular reaction products. It is therefore...

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Veröffentlicht in:	Archives of oral biology 1993-04, Vol.38 (4), p.357-359
Hauptverfasser:	Kiyoshima, T., Tsukuba, T., Kido, M.A., Tashiro, H., Yamamoto, K., Tanaka, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cathepsin B - analysis Cathepsin D - analysis cathepsins B and D Dentistry Fundamental and applied biological sciences. Psychology Immunoenzyme Techniques Immunohistochemistry Male Rats Rats, Wistar Skeleton and joints synovial lining cells Synovial Membrane - enzymology temporomandibular joint Temporomandibular Joint - enzymology Vertebrates: osteoarticular system, musculoskeletal system
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Zusammenfassung:	In 1 μm-thick serial cryosections, cathepsins B and D were found to coexist in both type A (macrophage-like) and type B (fibroblast-like) cells: the whole cytoplasm of the type A cells showed strong immunoreactivity, while the type B cells contained a few granular reaction products. It is therefore suggested that type A cells have a marked ability for intracellular digestion of organic materials.
ISSN:	0003-9969 1879-1506
DOI:	10.1016/0003-9969(93)90144-B