Evaluation of faecal calprotectin as a valuable non-invasive marker in distinguishing gut pathogens in young children with acute gastroenteritis

Aim: The aim of the study is to evaluate faecal calprotectin (f‐CP) in children ≤3 years of age with acute gastroenteritis (AG) as an early predictor of bacterial inflammation. Methods: We prospectively analysed f‐CP levels and diagnostic workup in 107 consecutive children (66 AG, 41 controls). Re...

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Veröffentlicht in:	Acta Paediatrica 2010-09, Vol.99 (9), p.1389-1395
Hauptverfasser:	Sýkora, Josef, Siala, Konrad, Huml, Michal, Varvařovská, Jana, Schwarz, Jan, Pomahačová, Renáta
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Acute gastroenteritis Age Bacterial Infections - diagnosis Biological and medical sciences Biomarkers - metabolism Blood C-reactive protein Case-Control Studies Child, Preschool Children Diagnosis, Differential Diarrhea Diarrhea - etiology Digestive tract Erythrocytes Faecal calprotectin Feces Feces - chemistry Female Fever Gastroenteritis Gastroenteritis - diagnosis Gastroenteritis - microbiology Gastroenteritis - virology General aspects Gut pathogens Humans Infant Leukocyte L1 Antigen Complex - metabolism Male Medical sciences Pathogens Prospective Studies ROC Curve Sedimentation Sensitivity and Specificity Virus Diseases - diagnosis Vomiting
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Zusammenfassung:	Aim: The aim of the study is to evaluate faecal calprotectin (f‐CP) in children ≤3 years of age with acute gastroenteritis (AG) as an early predictor of bacterial inflammation. Methods: We prospectively analysed f‐CP levels and diagnostic workup in 107 consecutive children (66 AG, 41 controls). Results: Children with bacterial AG (BAG) was found to have higher diarrheal frequency (p
ISSN:	0803-5253 1651-2227
DOI:	10.1111/j.1651-2227.2010.01843.x