A Diabetic Case of Hb Riyadh with a Low HbA1c Value
A 74-year-old male patient with diabetes mellitus and hypertension who had been treated for a long period was admitted to our hospital. Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 μmol/l respectively, while the concentration of glycat...
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| Veröffentlicht in: | Internal Medicine 1993, Vol.32(2), pp.128-132 |
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| container_issue | 2 |
| container_start_page | 128 |
| container_title | Internal Medicine |
| container_volume | 32 |
| creator | MAEZAWA, Yoshihiko YAMAUCHI, Masayoshi NAKABAYASHI, Tomoko TOSHIMA, Kyouichirou IKEDA, Kiyoko TODA, Gotaro |
| description | A 74-year-old male patient with diabetes mellitus and hypertension who had been treated for a long period was admitted to our hospital. Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 μmol/l respectively, while the concentration of glycated hemoglobin (HbA1c) was low (3.0%). High performance liquid chromatography and isoelectric focusing analysis of the patient's Hb disclosed abnormal Hb with the content being 41.3%. The structural analysis indicated that this abnormal Hb was Hb Riyadh [β120 (GH3) Lys→Asn]. The low value of HbA1c despite the high blood glucose level may be attributed to this abnormal hemoglobin. (Internal Medicine 32: 128-132, 1993) |
| doi_str_mv | 10.2169/internalmedicine.32.128 |
| format | Article |
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Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 μmol/l respectively, while the concentration of glycated hemoglobin (HbA1c) was low (3.0%). High performance liquid chromatography and isoelectric focusing analysis of the patient's Hb disclosed abnormal Hb with the content being 41.3%. The structural analysis indicated that this abnormal Hb was Hb Riyadh [β120 (GH3) Lys→Asn]. The low value of HbA1c despite the high blood glucose level may be attributed to this abnormal hemoglobin. 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Med.</addtitle><description>A 74-year-old male patient with diabetes mellitus and hypertension who had been treated for a long period was admitted to our hospital. Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 μmol/l respectively, while the concentration of glycated hemoglobin (HbA1c) was low (3.0%). High performance liquid chromatography and isoelectric focusing analysis of the patient's Hb disclosed abnormal Hb with the content being 41.3%. The structural analysis indicated that this abnormal Hb was Hb Riyadh [β120 (GH3) Lys→Asn]. The low value of HbA1c despite the high blood glucose level may be attributed to this abnormal hemoglobin. (Internal Medicine 32: 128-132, 1993)</description><subject>Aged</subject><subject>Biomarkers</subject><subject>Blood Glucose - analysis</subject><subject>Chromatography, High Pressure Liquid</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus, Type 2 - blood</subject><subject>Fructosamine</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>hemoglobin Riyadh</subject><subject>Hemoglobins, Abnormal - analysis</subject><subject>Hexosamines - analysis</subject><subject>Humans</subject><subject>Isoelectric Focusing</subject><subject>Male</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkMtOwzAQRS0EKqXwCQiv2KX4kcT2siqPIlUCoYqtNXEc6ipNwE5U9e9x1agL2MyM5t65Ix2E7iiZMpqrB9d01jdQb23pjGvslLMpZfIMjSlPVSIYz87RmCgqExbLJboKYUMIl0KxERrJjMSBjxGf4UcHhe2cwXMIFrcVXhT4w-2hXOOd69YY8LLdxeWMGvwJdW-v0UUFdbA3Q5-g1fPTar5Ilm8vr_PZMjFpKrqEFaqo0lLKkkKVM0GIKQtTlGkqBSlVBoZLkDTPjRJScWKKzOYCBLV5xSvKJ-j-GPvt25_ehk5vXTC2rqGxbR-0yESuJFHRKI5G49sQvK30t3db8HtNiT7Q0n9pac50pBUvb4cXfRG1092AJ-rvR30TOviyJx185FXbf7lUKXbIHkp8cbKaNXhtG_4L0oiGGA</recordid><startdate>1993</startdate><enddate>1993</enddate><creator>MAEZAWA, Yoshihiko</creator><creator>YAMAUCHI, Masayoshi</creator><creator>NAKABAYASHI, Tomoko</creator><creator>TOSHIMA, Kyouichirou</creator><creator>IKEDA, Kiyoko</creator><creator>TODA, Gotaro</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1993</creationdate><title>A Diabetic Case of Hb Riyadh with a Low HbA1c Value</title><author>MAEZAWA, Yoshihiko ; YAMAUCHI, Masayoshi ; NAKABAYASHI, Tomoko ; TOSHIMA, Kyouichirou ; IKEDA, Kiyoko ; TODA, Gotaro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-2b9bf4d88d1af62700cdbcbd44870d95ac38a8166c978930cb5e67a71e6f3f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Aged</topic><topic>Biomarkers</topic><topic>Blood Glucose - analysis</topic><topic>Chromatography, High Pressure Liquid</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus, Type 2 - blood</topic><topic>Fructosamine</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>hemoglobin Riyadh</topic><topic>Hemoglobins, Abnormal - analysis</topic><topic>Hexosamines - analysis</topic><topic>Humans</topic><topic>Isoelectric Focusing</topic><topic>Male</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MAEZAWA, Yoshihiko</creatorcontrib><creatorcontrib>YAMAUCHI, Masayoshi</creatorcontrib><creatorcontrib>NAKABAYASHI, Tomoko</creatorcontrib><creatorcontrib>TOSHIMA, Kyouichirou</creatorcontrib><creatorcontrib>IKEDA, Kiyoko</creatorcontrib><creatorcontrib>TODA, Gotaro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MAEZAWA, Yoshihiko</au><au>YAMAUCHI, Masayoshi</au><au>NAKABAYASHI, Tomoko</au><au>TOSHIMA, Kyouichirou</au><au>IKEDA, Kiyoko</au><au>TODA, Gotaro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Diabetic Case of Hb Riyadh with a Low HbA1c Value</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>1993</date><risdate>1993</risdate><volume>32</volume><issue>2</issue><spage>128</spage><epage>132</epage><pages>128-132</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 74-year-old male patient with diabetes mellitus and hypertension who had been treated for a long period was admitted to our hospital. Laboratory data on admission revealed high values for fasting blood sugar and fructosamine, 219 mg/dl and 389 μmol/l respectively, while the concentration of glycated hemoglobin (HbA1c) was low (3.0%). High performance liquid chromatography and isoelectric focusing analysis of the patient's Hb disclosed abnormal Hb with the content being 41.3%. The structural analysis indicated that this abnormal Hb was Hb Riyadh [β120 (GH3) Lys→Asn]. The low value of HbA1c despite the high blood glucose level may be attributed to this abnormal hemoglobin. (Internal Medicine 32: 128-132, 1993)</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>8507923</pmid><doi>10.2169/internalmedicine.32.128</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Internal Medicine, 1993, Vol.32(2), pp.128-132 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Aged Biomarkers Blood Glucose - analysis Chromatography, High Pressure Liquid diabetes mellitus Diabetes Mellitus, Type 2 - blood Fructosamine Glycated Hemoglobin A - analysis hemoglobin Riyadh Hemoglobins, Abnormal - analysis Hexosamines - analysis Humans Isoelectric Focusing Male |
| title | A Diabetic Case of Hb Riyadh with a Low HbA1c Value |
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