Conditioned Opioid Release in Ten-Day-Old Rats
Ten-day-old rats, for whom an orange scent predicted morphine injections at 5 days of age, exhibited a marked preference for orange that was fully naltrexone reversible. Moreover, such rats, when smelling orange during a heat-escape task, exhibited a higher pain threshold than control rats. Together...
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| Veröffentlicht in: | Behavioral neuroscience 1989-04, Vol.103 (2), p.423-428 |
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| container_title | Behavioral neuroscience |
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| creator | Kehoe, Priscilla Blass, Elliott M |
| description | Ten-day-old rats, for whom an orange scent predicted morphine injections at 5 days of age, exhibited a marked preference for orange that was fully naltrexone reversible. Moreover, such rats, when smelling orange during a heat-escape task, exhibited a higher pain threshold than control rats. Together, these findings suggest that the orange odor in conditioned rats caused a release of endogenous opioids that both sustained choice behavior and modulated pain systems. |
| doi_str_mv | 10.1037/0735-7044.103.2.423 |
| format | Article |
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Psychology</topic><topic>Infants (Animal)</topic><topic>Learning - physiology</topic><topic>Learning. Memory</topic><topic>Male</topic><topic>Morphine - pharmacology</topic><topic>Naltrexone - pharmacology</topic><topic>Nociceptors - physiology</topic><topic>Odors</topic><topic>Pain</topic><topic>Preferences</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Reaction Time - physiology</topic><topic>Receptors, Opioid - physiology</topic><topic>Smell - physiology</topic><topic>Synaptic Transmission - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kehoe, Priscilla</creatorcontrib><creatorcontrib>Blass, Elliott M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>APA PsycArticles®</collection><collection>ProQuest One Psychology</collection><collection>MEDLINE - Academic</collection><jtitle>Behavioral neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kehoe, Priscilla</au><au>Blass, Elliott M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conditioned Opioid Release in Ten-Day-Old Rats</atitle><jtitle>Behavioral neuroscience</jtitle><addtitle>Behav Neurosci</addtitle><date>1989-04</date><risdate>1989</risdate><volume>103</volume><issue>2</issue><spage>423</spage><epage>428</epage><pages>423-428</pages><issn>0735-7044</issn><eissn>1939-0084</eissn><coden>BENEDJ</coden><abstract>Ten-day-old rats, for whom an orange scent predicted morphine injections at 5 days of age, exhibited a marked preference for orange that was fully naltrexone reversible. Moreover, such rats, when smelling orange during a heat-escape task, exhibited a higher pain threshold than control rats. Together, these findings suggest that the orange odor in conditioned rats caused a release of endogenous opioids that both sustained choice behavior and modulated pain systems.</abstract><cop>Washington, DC</cop><pub>American Psychological Association</pub><pmid>2539839</pmid><doi>10.1037/0735-7044.103.2.423</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0735-7044 |
| ispartof | Behavioral neuroscience, 1989-04, Vol.103 (2), p.423-428 |
| issn | 0735-7044 1939-0084 |
| language | eng |
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| source | MEDLINE; EBSCOhost APA PsycARTICLES |
| subjects | Animal Animal behavior Animals Arousal - physiology Association Learning - physiology Biological and medical sciences Brain - physiology Choice Behavior Conditioning Conditioning, Classical - physiology Endogenous Opiates Endorphins - physiology Female Fundamental and applied biological sciences. Psychology Infants (Animal) Learning - physiology Learning. Memory Male Morphine - pharmacology Naltrexone - pharmacology Nociceptors - physiology Odors Pain Preferences Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Inbred Strains Reaction Time - physiology Receptors, Opioid - physiology Smell - physiology Synaptic Transmission - drug effects |
| title | Conditioned Opioid Release in Ten-Day-Old Rats |
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