Acrosome reaction in Chlamydia-positive and negative patients

Chlamydia trachomatis infections might have a detrimental effect on various sperm functions. Data concerning the effect of C. trachomatis on the capacitation activity of sperms are lacking. The study was undertaken to evaluate whether chlamydial infection influences acromsome reaction (AR). Three groups of men were investigated for ARs –Chlamydia negative (n = 46) and positive (n = 30) patients, and healthy men (n = 53) undergoing vasectomy. The fluorescence technique for the evaluation of AR was applied. The normal range for the induction of AR was assumed ΔAR > 12.5% for this technique. Seminal plasma was examined for IgA antibodies against C. trachomatis. There was a significant difference in AR between healthy volunteers, Chlamydia‐negative and Chlamydia‐positive patients. ΔARs were 15.8 ± 1.6% in healthy volunteers versus 12.15 ± 2.4% in Chlamydia‐negative and 9.08 ± 1.8% in Chlamydia‐postive patients, respectively (P