Fluorescent diagnostics of human gastric cancer and sodium fluorescein accumulation in experimental gastric cancer in rats
Patients (459) with chronic gastritis, ulcers, polyposis and different types of gastric cancers were examined by endoscopic fluorescent technique using a special drug based on the sodium salt of fluorescein (Fl). Eighty-five percent of gastric cancers showed positive fluorescence. The Fl distributio...
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| Veröffentlicht in: | Cancer letters 1993-04, Vol.69 (2), p.117-121 |
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| container_end_page | 121 |
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| container_issue | 2 |
| container_start_page | 117 |
| container_title | Cancer letters |
| container_volume | 69 |
| creator | Braginskaja, O.V. Lazarev, V.V. Polsachev, V.I. Rubin, L.B. Stoskii, V.E. |
| description | Patients (459) with chronic gastritis, ulcers, polyposis and different types of gastric cancers were examined by endoscopic fluorescent technique using a special drug based on the sodium salt of fluorescein (Fl). Eighty-five percent of gastric cancers showed positive fluorescence. The Fl distribution in the stomach of the rat with induced gastric cancer was examined. In all cases the level of Fl fluorescence in the tumor was higher than in the adjacent normal tissues of the stomach. Thus, all the obtained results confirm the selective accumulation of Fl in tumors of the stomach. |
| doi_str_mv | 10.1016/0304-3835(93)90163-4 |
| format | Article |
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Eighty-five percent of gastric cancers showed positive fluorescence. The Fl distribution in the stomach of the rat with induced gastric cancer was examined. In all cases the level of Fl fluorescence in the tumor was higher than in the adjacent normal tissues of the stomach. 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Eighty-five percent of gastric cancers showed positive fluorescence. The Fl distribution in the stomach of the rat with induced gastric cancer was examined. In all cases the level of Fl fluorescence in the tumor was higher than in the adjacent normal tissues of the stomach. Thus, all the obtained results confirm the selective accumulation of Fl in tumors of the stomach.</description><subject>Animals</subject><subject>diagnostics of cancer</subject><subject>Female</subject><subject>Fluorescein</subject><subject>Fluoresceins - metabolism</subject><subject>fluorescent dyes</subject><subject>Gastritis - diagnosis</subject><subject>human gastric cancer</subject><subject>induced tumors</subject><subject>Neoplasms, Experimental - metabolism</subject><subject>Rats</subject><subject>Spectrometry, Fluorescence</subject><subject>Stomach Diseases - diagnosis</subject><subject>Stomach Neoplasms - diagnosis</subject><subject>Ulcer - diagnosis</subject><issn>0304-3835</issn><issn>1872-7980</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9vFSEUxYmxqc_Wb6AJC2PsYiwMMMDGxDT2T9LEja4JA5eKmRmeMNO0_fQyvudbuOiKcM-55977Q-gtJZ8ood05YYQ3TDHxUbMzXSus4S_QhirZNlIr8hJtDpZX6HUpvwghgktxjI4V14ITskFPl8OSMhQH04x9tHdTKnN0BaeAfy6jnfCdLXOODjs7OcjYTh6X5OMy4vCvNU7YOreMy2DnmCZc__CwhRzHmmqH_yOqnO1cTtFRsEOBN_v3BP24_Pr94rq5_XZ1c_HltnFMdXPTSlCSkQCCeAF1fR_6ekfX9-BZG1otveqBaeVZLXLbUUE97QPRklHgjJ2gD7vcbU6_FyizGWNdehjsBGkpRgopiGxXI98ZXU6lZAhmW0-w-dFQYlbkZuVpVp5GM_MXueG17d0-f-lH8IemPeOqv9_rtjg7hFwpxHKwcUWo7tbpn3c2qCzuI2RTXIQKzMcMbjY-xef3-AO2TZ8Z</recordid><startdate>19930430</startdate><enddate>19930430</enddate><creator>Braginskaja, O.V.</creator><creator>Lazarev, V.V.</creator><creator>Polsachev, V.I.</creator><creator>Rubin, L.B.</creator><creator>Stoskii, V.E.</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19930430</creationdate><title>Fluorescent diagnostics of human gastric cancer and sodium fluorescein accumulation in experimental gastric cancer in rats</title><author>Braginskaja, O.V. ; Lazarev, V.V. ; Polsachev, V.I. ; Rubin, L.B. ; Stoskii, V.E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-27e8730fe50d5e475dfb0056bbed32f297d8be398d356b4a6151d1bf09731e433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Animals</topic><topic>diagnostics of cancer</topic><topic>Female</topic><topic>Fluorescein</topic><topic>Fluoresceins - metabolism</topic><topic>fluorescent dyes</topic><topic>Gastritis - diagnosis</topic><topic>human gastric cancer</topic><topic>induced tumors</topic><topic>Neoplasms, Experimental - metabolism</topic><topic>Rats</topic><topic>Spectrometry, Fluorescence</topic><topic>Stomach Diseases - diagnosis</topic><topic>Stomach Neoplasms - diagnosis</topic><topic>Ulcer - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Braginskaja, O.V.</creatorcontrib><creatorcontrib>Lazarev, V.V.</creatorcontrib><creatorcontrib>Polsachev, V.I.</creatorcontrib><creatorcontrib>Rubin, L.B.</creatorcontrib><creatorcontrib>Stoskii, V.E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Braginskaja, O.V.</au><au>Lazarev, V.V.</au><au>Polsachev, V.I.</au><au>Rubin, L.B.</au><au>Stoskii, V.E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fluorescent diagnostics of human gastric cancer and sodium fluorescein accumulation in experimental gastric cancer in rats</atitle><jtitle>Cancer letters</jtitle><addtitle>Cancer Lett</addtitle><date>1993-04-30</date><risdate>1993</risdate><volume>69</volume><issue>2</issue><spage>117</spage><epage>121</epage><pages>117-121</pages><issn>0304-3835</issn><eissn>1872-7980</eissn><coden>CALEDQ</coden><abstract>Patients (459) with chronic gastritis, ulcers, polyposis and different types of gastric cancers were examined by endoscopic fluorescent technique using a special drug based on the sodium salt of fluorescein (Fl). 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| fulltext | fulltext |
| identifier | ISSN: 0304-3835 |
| ispartof | Cancer letters, 1993-04, Vol.69 (2), p.117-121 |
| issn | 0304-3835 1872-7980 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75750723 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals diagnostics of cancer Female Fluorescein Fluoresceins - metabolism fluorescent dyes Gastritis - diagnosis human gastric cancer induced tumors Neoplasms, Experimental - metabolism Rats Spectrometry, Fluorescence Stomach Diseases - diagnosis Stomach Neoplasms - diagnosis Ulcer - diagnosis |
| title | Fluorescent diagnostics of human gastric cancer and sodium fluorescein accumulation in experimental gastric cancer in rats |
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