First trimester fasting hyperglycemia as a predictor for the development of gestational diabetes mellitus

Abstract Objective Screening for gestational diabetes mellitus (GDM) is usually done at 24–28 weeks of gestation. Our goal was to study the association between first trimester fasting plasma glucose level and GDM risk and to evaluate its efficacy as a screening test for GDM in comparison to a traditional risk factor, pregestational body mass index (BMI). Study design The charts of all patients who delivered in our hospital between June 2001 and June 2006 were reviewed. Only subjects with a singleton pregnancy and a recorded first trimester fasting glucose level and BMI were studied. Women with pregestational diabetes mellitus, fasting glucose level >105 mg/dl or delivery at