Prevalence of Multivessel Coronary Artery Disease in Patients With Diabetes Mellitus Plus Hypothyroidism, in Patients With Diabetes Mellitus Without Hypothyroidism, and in Patients With No Diabetes Mellitus or Hypothyroidism

Background. We report the prevalence of significant multivessel coronary artery disease (CAD) (>50% stenosis) in patients with diabetes plus hypothyroidism, in patients with diabetes without hypothyroidism, and in patients without diabetes or hypothyroidism who had significant CAD documented by coronary angiography. Methods. We performed a retrospective analysis in 100 patients selected randomly with significant CAD documented by coronary angiography to investigate the prevalence of significant multivessel CAD in patients with diabetes, in patients with hypothyroidism, and in patients without diabetes or hypothyroidism. Results. Significant 3–4-vessel CAD was present in 9 of 10 patients (90%), mean age 73 ± 11 years, with diabetes plus hypothyroidism, in 10 of 25 patients (40%), mean age 63 ± 9 years, with diabetes without hypothyroidism, and in 10 of 65 patients (15%), mean age 68 ± 12 years, without diabetes or hypothyroidism (p