Treatment of Bronchiolitis

To the Editor: More than 20 years have elapsed since Wohl and Chernick speculated about the possible clinical efficacy of inhaled epinephrine in the treatment of infants with acute bronchiolitis. 1 It turns out, according to the study reported by Wainwright et al. (July 3 issue), 2 that this intervention, which seemed sensible, provides little benefit. Now, physiologically orientated Wohl and Chernick are at it again, speculating in an accompanying editorial that α-adrenergic nose drops before feeding might be helpful. 3 Because the authors and the Journal are so highly respected, our fear is that this conjecture will be taken as a recommendation. . . .