TERPESTACIN, A NEW SYNCYTIUM FORMATION INHIBITOR FROM Arthrinium sp

Terpestacin, a new antibiotic which inhibits syncytium formation, was isolated from Arthrinium sp. FA1744 (ATCC 74132). The structure of terpestacin was elucidated as a bicyclic sesterterpene on the basis of spectroscopic data and chemical derivatization.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 1993/03/25, Vol.46(3), pp.367-373
Hauptverfasser:	OKA, MASAHISA, IIMURA, SEIJI, TENMYO, OSAMU, SAWADA, YOSUKE, SUGAWARA, MASARU, OHKUSA, NORIYUKI, YAMAMOTO, HARUAKI, KAWANO, KIMIO, HU, SHIU-LOK, FUKAGAWA, YASUO, OKI, TOSHIKAZU
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Bridged Bicyclo Compounds - chemistry Bridged Bicyclo Compounds - isolation & purification Bridged Bicyclo Compounds - pharmacology Cell Line Fermentation Giant Cells - drug effects Magnetic Resonance Spectroscopy Medical sciences Microbial Sensitivity Tests Mitosporic Fungi - chemistry Pharmacology. Drug treatments
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Beschreibung
Zusammenfassung:	Terpestacin, a new antibiotic which inhibits syncytium formation, was isolated from Arthrinium sp. FA1744 (ATCC 74132). The structure of terpestacin was elucidated as a bicyclic sesterterpene on the basis of spectroscopic data and chemical derivatization.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.46.367