Synthesis of plasmalopsychosines A and B, two novel lysosphingolipids found in human brain

The purpose of the present work is to provide synthetic samples of plasmalopsychosines A and B (PP-A and PP-B) to facilitate protein kinase C related studies. This paper describes the synthesis of PP-A, PP-B, and a structural analogue of PP-B.

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Bibliographische Detailangaben
Veröffentlicht in:	Carbohydrate research 1993-03, Vol.241, p.301-307
Hauptverfasser:	Sadozai, Khalid Khan, Anand, Jasbir Kaur, Nudelman, Edward D., Hakomori, Sen-itiroh
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Chemistry Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry Chromatography, High Pressure Liquid Chromatography, Thin Layer Exact sciences and technology Glycosphingolipids - chemical synthesis Humans Magnetic Resonance Spectroscopy Organic chemistry Preparations and properties Protein Kinase C - antagonists & inhibitors Psychosine - analogs & derivatives Psychosine - chemical synthesis
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Beschreibung
Zusammenfassung:	The purpose of the present work is to provide synthetic samples of plasmalopsychosines A and B (PP-A and PP-B) to facilitate protein kinase C related studies. This paper describes the synthesis of PP-A, PP-B, and a structural analogue of PP-B.
ISSN:	0008-6215 1873-426X
DOI:	10.1016/0008-6215(93)80120-4