Radioimmunoassay of anti-albumin autoantibodies in human sera

A radioimmunoassay using protein A-containing staphylococci is described in which radio-iodinated polymerized albumin is mixed with the sera to be tested and the resulting immune complex is adsorbed on to Staphylococci bacteria. The assay is used to detect autoantibodies against human albumin in ser...

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Veröffentlicht in:Journal of immunological methods 1981-01, Vol.42 (2), p.187-193
Hauptverfasser: Mihǎescu, Silvia, Lenkei, Rodica, Gheţie, V.
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container_title Journal of immunological methods
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creator Mihǎescu, Silvia
Lenkei, Rodica
Gheţie, V.
description A radioimmunoassay using protein A-containing staphylococci is described in which radio-iodinated polymerized albumin is mixed with the sera to be tested and the resulting immune complex is adsorbed on to Staphylococci bacteria. The assay is used to detect autoantibodies against human albumin in sera of normal subjects and patients with liver diseases.
doi_str_mv 10.1016/0022-1759(81)90148-4
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Autoantibodies - analysis
Hepatitis, Viral, Human - immunology
Humans
Liver Cirrhosis - immunology
Liver Diseases - immunology
Polymers
Radioimmunoassay - methods
Serum Albumin - immunology
Staphylococcal Protein A - immunology
Staphylococcus - immunology
title Radioimmunoassay of anti-albumin autoantibodies in human sera
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