Radioimmunoassay of anti-albumin autoantibodies in human sera

A radioimmunoassay using protein A-containing staphylococci is described in which radio-iodinated polymerized albumin is mixed with the sera to be tested and the resulting immune complex is adsorbed on to Staphylococci bacteria. The assay is used to detect autoantibodies against human albumin in ser...

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Veröffentlicht in:	Journal of immunological methods 1981-01, Vol.42 (2), p.187-193
Hauptverfasser:	Mihǎescu, Silvia, Lenkei, Rodica, Gheţie, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantibodies - analysis Hepatitis, Viral, Human - immunology Humans Liver Cirrhosis - immunology Liver Diseases - immunology Polymers Radioimmunoassay - methods Serum Albumin - immunology Staphylococcal Protein A - immunology Staphylococcus - immunology
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Beschreibung
Zusammenfassung:	A radioimmunoassay using protein A-containing staphylococci is described in which radio-iodinated polymerized albumin is mixed with the sera to be tested and the resulting immune complex is adsorbed on to Staphylococci bacteria. The assay is used to detect autoantibodies against human albumin in sera of normal subjects and patients with liver diseases.
ISSN:	0022-1759 1872-7905
DOI:	10.1016/0022-1759(81)90148-4