The comparative phytochemistry of the genus Erythroxylon

Recent research suggests that, in addition to the well-documented occurrence of significant quantities of cocaine and related alkaloids in a limited number of species, the genus Erythroxylon will prove to be a rich source of tropane alkaloids. These bases are esters of a range of acids with tropine, 3α, 6βt-dihydroxy tropane and 3α,6β,7β-trihydroxytropane; the numbers are further increased by nor-derivatives, and stereoisomerism involving the C-3 hydroxyl of the tropane skeleton. The diterpenes of the genus also appear worthy of further study.