The effect of adrenaline on peripheral vascular resistance at different temperatures in a hind part preparation of rainbow trout ( Salmo Gairdnerii R.)

1. Preparations of rainbow trout were perfused with oxygenated Hepes buffered dextran solution, and the mean perfusion pressures were monitored. 2. Adrenaline caused a maximal constriction in the range of 64–92 mm Hg. 3. Adrenaline effect of PRU 100 was greater at 5°C than at 0.5 or 10°C. 4. The adr...

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Veröffentlicht in:Comparative biochemistry and physiology. C, Comparative pharmacology Comparative pharmacology, 1981, Vol.69 (1), p.157-159
Hauptverfasser: Moen, Kjell A., Wisnes, Alex R., Elsayed, Else Aaker, Eliassen, Einar E.
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Sprache:eng
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Zusammenfassung:1. Preparations of rainbow trout were perfused with oxygenated Hepes buffered dextran solution, and the mean perfusion pressures were monitored. 2. Adrenaline caused a maximal constriction in the range of 64–92 mm Hg. 3. Adrenaline effect of PRU 100 was greater at 5°C than at 0.5 or 10°C. 4. The adrenaline affinity (pD 2) was highest at 0.5°C, but not significantly different at 5, 10 or 18°C. 5. Our results indicate that the potential regulatory efficiency of adrenaline on the peripheral circulation is highest at the normal habitat temperature of the fish (5–8°C).
ISSN:0306-4492
DOI:10.1016/0306-4492(81)90120-9