Biochemical Model Reactions on the Prooxidative Activity of Homocysteine

The sulfur amino acid homocysteine has recently been addressed as marker for vessel damaging and atherosclerotic dispositions. The atherogenic index has been correlated with the one of cholesterol and is significantly higher in cholesterinemic as compared to normal lipidemic persons. In the present...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Zeitschrift für Naturforschung C. A journal of biosciences 1993-01, Vol.48 (1), p.58-62
Hauptverfasser:	Preibisch, Gudrun, Kiiffner, Christina, Elstner, Erich F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoacids, peptides. Hormones. Neuropeptides Analytical, structural and metabolic biochemistry Atherogenesis Biological and medical sciences Copper - pharmacology Cysteine - chemistry Cysteine - pharmacology Erythrocytes - drug effects Erythrocytes - physiology Fundamental and applied biological sciences. Psychology Hemolysis - drug effects Homocysteine Homocysteine - chemistry Homocysteine - pharmacology Humans Iron - pharmacology Kinetics Methionine - analogs & derivatives Methionine - chemistry Oxygen Activation Proteins Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The sulfur amino acid homocysteine has recently been addressed as marker for vessel damaging and atherosclerotic dispositions. The atherogenic index has been correlated with the one of cholesterol and is significantly higher in cholesterinemic as compared to normal lipidemic persons. In the present communication biochemical model reactions are presented indicating the prooxidative activity of homocysteine where a cooperative effect with the transition-metals copper and iron is indicated.
ISSN:	0939-5075 1865-7125
DOI:	10.1515/znc-1993-1-211