Case Report of a 2-Year-Old Boy With Takayasu’s Arteritis: An Atypical, Severe Presentation of a Rare Disease

Takayasu’s arteritis is a granulomatous giant-cell arteritis of the aorta and its major branches. It primarily affects East Asian women in their second or third decade of life but is well known to affect all ethnicities across the world. Given its systemic nature, Takayasu’s arteritis has multiorgan...

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Veröffentlicht in:Pediatric cardiology 2010-10, Vol.31 (7), p.1089-1092
Hauptverfasser: Berman, Darren P., Lewis, Alan B., Kung, Grace C.
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Sprache:eng
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Zusammenfassung:Takayasu’s arteritis is a granulomatous giant-cell arteritis of the aorta and its major branches. It primarily affects East Asian women in their second or third decade of life but is well known to affect all ethnicities across the world. Given its systemic nature, Takayasu’s arteritis has multiorgan involvement, with the majority of disease morbidity related to the cardiovascular, central nervous, and renal systems. This report describes an unusual presentation of Takayasu’s arteritis in a 2½-year-old boy. This is the first report in the literature describing the presence of both severe aortic regurgitation and diffuse coronary artery involvement in a patient so young.
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-010-9742-5