Leukemic optic neuropathy

Leukemic optic neuropathy

The clinical course and ophthalmic manifestations of an eight year old child with acute undifferentiated leukemia and unilateral blindness secondary to leukemic optic nerve head infiltration are described. At autopsy the involved nerve head and peripapillary retina demonstrated massive leukemic cell...

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Veröffentlicht in:International ophthalmology 1981-03, Vol.3 (2), p.111-116
Hauptverfasser: Brown, G C, Shields, J A, Augsburger, J J, Serota, F T, Koch, P
Format: Artikel
Sprache:eng
Schlagworte:
Blindness - etiology
Bone Marrow Transplantation
Child
Humans
Leukemia, Lymphoid - complications
Leukemia, Lymphoid - therapy
Male
Optic Nerve Diseases - etiology
Retina - pathology
Retinal Vessels - pathology
Transplantation, Homologous
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Zusammenfassung:The clinical course and ophthalmic manifestations of an eight year old child with acute undifferentiated leukemia and unilateral blindness secondary to leukemic optic nerve head infiltration are described. At autopsy the involved nerve head and peripapillary retina demonstrated massive leukemic cell infiltration and hemorrhagic necrosis. This manifestation of leukemia is quite uncommon and prognosis for life in such cases is poor with existing methods of therapy.
ISSN:0165-5701
1573-2630
DOI:10.1007/BF00133423