Effect of picrate on potassium conductance of neurons in Helix pomatia
1. 1. Neurons of Helix pomatia were exposed to 4 mM Na-picrate. 2. 2. The cells hyperpolarized by 18 mV. 3. 3. Simultaneously, the steady membrane resistance decreased and the steady I–V curve of the cells changed towards increased slope conductance. 4. 4. The hyperpolarization reversed at −84 mV. 5...
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| Veröffentlicht in: | Comparative biochemistry and physiology. C, Comparative pharmacology Comparative pharmacology, 1981, Vol.68 (2), p.243-245 |
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| container_end_page | 245 |
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| container_issue | 2 |
| container_start_page | 243 |
| container_title | Comparative biochemistry and physiology. C, Comparative pharmacology |
| container_volume | 68 |
| creator | Christoffersen, G.R.J. |
| description | 1.
1. Neurons of
Helix pomatia were exposed to 4 mM Na-picrate.
2.
2. The cells hyperpolarized by 18 mV.
3.
3. Simultaneously, the steady membrane resistance decreased and the steady I–V curve of the cells changed towards increased slope conductance.
4.
4. The hyperpolarization reversed at −84 mV.
5.
5. A picrate induced increase of clamp current at the resting membrane potential could be accounted for through an increased K
+ conductance. |
| doi_str_mv | 10.1016/0306-4492(81)90024-1 |
| format | Article |
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1. Neurons of
Helix pomatia were exposed to 4 mM Na-picrate.
2.
2. The cells hyperpolarized by 18 mV.
3.
3. Simultaneously, the steady membrane resistance decreased and the steady I–V curve of the cells changed towards increased slope conductance.
4.
4. The hyperpolarization reversed at −84 mV.
5.
5. A picrate induced increase of clamp current at the resting membrane potential could be accounted for through an increased K
+ conductance.</description><identifier>ISSN: 0306-4492</identifier><identifier>DOI: 10.1016/0306-4492(81)90024-1</identifier><identifier>PMID: 6112112</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>Animals ; Cell Membrane - physiology ; Electric Conductivity ; Helix (Snails) - cytology ; Membrane Potentials - drug effects ; Neurons - drug effects ; Neurons - physiology ; Picrates - pharmacology ; Potassium - metabolism</subject><ispartof>Comparative biochemistry and physiology. C, Comparative pharmacology, 1981, Vol.68 (2), p.243-245</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-e4d6a1ae7b20aa8eaaa8b55da494db615694bf0451b3748692897e32c3f93a003</citedby><cites>FETCH-LOGICAL-c357t-e4d6a1ae7b20aa8eaaa8b55da494db615694bf0451b3748692897e32c3f93a003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6112112$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christoffersen, G.R.J.</creatorcontrib><title>Effect of picrate on potassium conductance of neurons in Helix pomatia</title><title>Comparative biochemistry and physiology. C, Comparative pharmacology</title><addtitle>Comp Biochem Physiol C</addtitle><description>1.
1. Neurons of
Helix pomatia were exposed to 4 mM Na-picrate.
2.
2. The cells hyperpolarized by 18 mV.
3.
3. Simultaneously, the steady membrane resistance decreased and the steady I–V curve of the cells changed towards increased slope conductance.
4.
4. The hyperpolarization reversed at −84 mV.
5.
5. A picrate induced increase of clamp current at the resting membrane potential could be accounted for through an increased K
+ conductance.</description><subject>Animals</subject><subject>Cell Membrane - physiology</subject><subject>Electric Conductivity</subject><subject>Helix (Snails) - cytology</subject><subject>Membrane Potentials - drug effects</subject><subject>Neurons - drug effects</subject><subject>Neurons - physiology</subject><subject>Picrates - pharmacology</subject><subject>Potassium - metabolism</subject><issn>0306-4492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFKxDAQhnNQ1nX1DRR6Ej1UkyZNm4sgy64rLHjRc5imU4i0TU1a0bc36y57FIYZmPnnH-Yj5IrRe0aZfKCcylQIld2W7E5RmomUnZD5sX1GzkP4oJSpkpczMpOMZTHmZL1qGjRj4ppksMbDiInrk8GNEIKdusS4vp7MCL3BnabHybs-JLZPNtja76jsYLRwQU4baANeHuqCvK9Xb8tNun19flk-bVPD82JMUdQSGGBRZRSgRIipyvMahBJ1JVkulagaKnJW8UKUUmWlKpBnhjeKA6V8QW72voN3nxOGUXc2GGxb6NFNQRe5FJnKeRSKvdB4F4LHRg_eduB_NKN6h0zv2OgdG10y_YdMs7h2ffCfqg7r49KBV5w_7ucYn_yy6HUwFiOc2vqIUdfO_n_gF8EAfCY</recordid><startdate>1981</startdate><enddate>1981</enddate><creator>Christoffersen, G.R.J.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1981</creationdate><title>Effect of picrate on potassium conductance of neurons in Helix pomatia</title><author>Christoffersen, G.R.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-e4d6a1ae7b20aa8eaaa8b55da494db615694bf0451b3748692897e32c3f93a003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Animals</topic><topic>Cell Membrane - physiology</topic><topic>Electric Conductivity</topic><topic>Helix (Snails) - cytology</topic><topic>Membrane Potentials - drug effects</topic><topic>Neurons - drug effects</topic><topic>Neurons - physiology</topic><topic>Picrates - pharmacology</topic><topic>Potassium - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christoffersen, G.R.J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Comparative biochemistry and physiology. C, Comparative pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christoffersen, G.R.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of picrate on potassium conductance of neurons in Helix pomatia</atitle><jtitle>Comparative biochemistry and physiology. C, Comparative pharmacology</jtitle><addtitle>Comp Biochem Physiol C</addtitle><date>1981</date><risdate>1981</risdate><volume>68</volume><issue>2</issue><spage>243</spage><epage>245</epage><pages>243-245</pages><issn>0306-4492</issn><abstract>1.
1. Neurons of
Helix pomatia were exposed to 4 mM Na-picrate.
2.
2. The cells hyperpolarized by 18 mV.
3.
3. Simultaneously, the steady membrane resistance decreased and the steady I–V curve of the cells changed towards increased slope conductance.
4.
4. The hyperpolarization reversed at −84 mV.
5.
5. A picrate induced increase of clamp current at the resting membrane potential could be accounted for through an increased K
+ conductance.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>6112112</pmid><doi>10.1016/0306-4492(81)90024-1</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0306-4492 |
| ispartof | Comparative biochemistry and physiology. C, Comparative pharmacology, 1981, Vol.68 (2), p.243-245 |
| issn | 0306-4492 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75642953 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Cell Membrane - physiology Electric Conductivity Helix (Snails) - cytology Membrane Potentials - drug effects Neurons - drug effects Neurons - physiology Picrates - pharmacology Potassium - metabolism |
| title | Effect of picrate on potassium conductance of neurons in Helix pomatia |
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