A Rapid and Specific Method for Measuring Chloramphenicol Degradation in Aqueous Solution Following Autoclaving
An HPLC Method is reported for the measurement of chloramphenicol and its degradation product following autoclaving. The procedure, using a reversed-phase column and potassium phosphate solution as the solvent,is shown to be suitable for monitoring chloramphenicol degradation in intrathecal injectio...
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Veröffentlicht in: | Journal of chromatographic science 1981-02, Vol.19 (2), p.96-97 |
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container_title | Journal of chromatographic science |
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creator | Lee, M.G. Dawes, S. Mannion, P. |
description | An HPLC Method is reported for the measurement of chloramphenicol and its degradation product following autoclaving. The procedure, using a reversed-phase column and potassium phosphate solution as the solvent,is shown to be suitable for monitoring chloramphenicol degradation in intrathecal injection after sterilization. |
doi_str_mv | 10.1093/chromsci/19.2.96 |
format | Article |
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ispartof | Journal of chromatographic science, 1981-02, Vol.19 (2), p.96-97 |
issn | 0021-9665 1945-239X |
language | eng |
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source | MEDLINE; Oxford University Press Journals Digital Archive Legacy |
subjects | Chloramphenicol - analysis Chromatography, High Pressure Liquid - methods Drug Stability Drug Storage Sterilization Temperature |
title | A Rapid and Specific Method for Measuring Chloramphenicol Degradation in Aqueous Solution Following Autoclaving |
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