Severe generalized (Charcot-like) joint destruction in juvenile rheumatoid arthritis

Although severe polyarticular joint destruction is rarely observed in children with juvenile rheumatoid arthritis (JRA), it occurred in two patients, a 5-year-old girl and an 11-year-old boy. Histopathologic examinations revealed changes typical of JRA with fragments of cartilage imbedded in synovia...

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Veröffentlicht in:	Clinical orthopaedics and related research 1981-03, Vol.155 (155), p.75-80
Hauptverfasser:	Rothschild, B M, Hanissian, A S
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Juvenile - complications Arthritis, Juvenile - pathology Arthropathy, Neurogenic - complications Arthropathy, Neurogenic - pathology Cartilage, Articular - pathology Child Child, Preschool Female Finger Joint - pathology Humans Male Metacarpophalangeal Joint - pathology Shoulder Joint - pathology Synovial Membrane - pathology Wrist Joint - pathology
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Zusammenfassung:	Although severe polyarticular joint destruction is rarely observed in children with juvenile rheumatoid arthritis (JRA), it occurred in two patients, a 5-year-old girl and an 11-year-old boy. Histopathologic examinations revealed changes typical of JRA with fragments of cartilage imbedded in synovial membrane. Such fragments are usually seen in adults with neuropathic joint disease. Steroid hormone treatment may be implicated in the pathogenesis of joint destruction in children.
ISSN:	0009-921X
DOI:	10.1097/00003086-198103000-00014