Growth factors: Regulation of normal and neoplastic growth

This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest con...

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Veröffentlicht in:	The Journal of pathology 1993-02, Vol.169 (2), p.191-201
Hauptverfasser:	Pusztai, L., Lewis, C. E., Lorenzen, J., McGee, J. O'D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences carcinogenesis Cell Division - physiology General aspects (metabolism, cell proliferation, established cell line...) Growth factors Growth Inhibitors - metabolism Growth Substances - physiology Humans Medical sciences Neoplasia Neoplasms - metabolism Tumor cell Tumors
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Beschreibung
Zusammenfassung:	This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.
ISSN:	0022-3417 1096-9896
DOI:	10.1002/path.1711690204