Cell-mediated hyperacute rejection: II. The early events

Cell-mediated hyperacute rejection: II. The early events

The “white graft” reaction, the most severe form of cell-mediated hyperacute rejection reactions, results in early graft death, demonstrable by failure of syngeneic retransplantation beginning about 24 hr after placement onto the sensitized recipients. This is preceded by ultrastructural necrotic ch...

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Veröffentlicht in:Cellular immunology 1981-03, Vol.59 (1), p.219-224
Hauptverfasser: Moatamed, F., Taylor, J.V., Emam, M., Eichwald, E.J.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Endothelium - ultrastructure
Female
Graft Rejection
Immunity, Cellular
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Skin - ultrastructure
Time Factors
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Zusammenfassung:The “white graft” reaction, the most severe form of cell-mediated hyperacute rejection reactions, results in early graft death, demonstrable by failure of syngeneic retransplantation beginning about 24 hr after placement onto the sensitized recipients. This is preceded by ultrastructural necrotic changes of graft endothelial cells, beginning about 6 hr after graft placement. The likely rejection mechanisms and immune pathways are discussed.
ISSN:0008-8749
1090-2163
DOI:10.1016/0008-8749(81)90449-4