Normal excretion of m-hydroxymandelic acid in hypertensive patients

o-Hydroxymandelic acid (OHMA), m-hydroxymandelic acid (MHMA) and p-hydroxymandelic acid (PHMA) were measured in the urine of 42 normotensive and 54 hypertensive patients. Patients having high urinary MHMA levels were all found to be ingesting medications containing m-synephrine (phenylephrine). Thes...

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Veröffentlicht in:Clinica chimica acta 1981-01, Vol.109 (2), p.125-131
Hauptverfasser: Crowley, Jan R., Couch, Margaret W., Williams, Clyde M., Threatte, Rose M., Fregly, Melvin J.
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Sprache:eng
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Zusammenfassung:o-Hydroxymandelic acid (OHMA), m-hydroxymandelic acid (MHMA) and p-hydroxymandelic acid (PHMA) were measured in the urine of 42 normotensive and 54 hypertensive patients. Patients having high urinary MHMA levels were all found to be ingesting medications containing m-synephrine (phenylephrine). These patients also had high levels of urinary m-synephrine which was excreted as the glucuronide. When patients ingesting m-synephrine were excluded from the analysis, no significant differences were observed between the two groups for the urinary excretion of OHMA, MHMA and PHMA.
ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(81)90326-0