Influence of oral calcium medication on nasal resistance in the nasal allergen provocation test

Although calcium has been used for several decades to treat allergic diseases of the skin and respiratory tract, controlled studies demonstrating the action of oral preparations in allergic rhinitis are lacking. This placebo-controlled, double-blind, crossover study shows that 1000 mg calcium admini...

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Veröffentlicht in:Journal of allergy and clinical immunology 1993-02, Vol.91 (2), p.599-604
Hauptverfasser: Bachert, Claus, Drechsler, Sabine, Hauser, Ulrich, Imhoff, Walter, Welzel, Dieter
Format: Artikel
Sprache:eng
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Zusammenfassung:Although calcium has been used for several decades to treat allergic diseases of the skin and respiratory tract, controlled studies demonstrating the action of oral preparations in allergic rhinitis are lacking. This placebo-controlled, double-blind, crossover study shows that 1000 mg calcium administered orally significantly inhibits the allergen-induced swelling of the nasal mucosa in the allergen provocation test. Sneezing and secretion, which are allergic symptoms, were not reduced. This study is the first to confirm the positive effect of oral calcium on a symptom of allergic rhinitis.
ISSN:0091-6749
1097-6825
DOI:10.1016/0091-6749(93)90265-H