Circulating concentrations of specific placental proteins (human chorionic gonadotropin, pregnancy-specific beta-1 glycoprotein, and placental protein 5) in untreated gestational trophoblastic tumors

Circulating concentrations of specific placental proteins (human chorionic gonadotropin, pregnancy-specific beta-1 glycoprotein, and placental protein 5) in untreated gestational trophoblastic tumors

Serum levels of human chorionic gonadotropin (hCG), pregnancy-specific beta-1-glycoprotein (SP1), and placental protein 5 (PP5) were measured prior to treatment in 14 patients with hydatidiform mole and in nine patients with choriocarcinoma. Measurement of circulating levels of SP1 and PP5, but not...

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Veröffentlicht in:American journal of obstetrics and gynecology 1981-03, Vol.139 (6), p.702-704
Hauptverfasser: Lee, Jau Nan, Salem, Hossam T., Al-Ani, Abdullah T.M., Chard, Tim, Huang, Su Cheng, Ouyang, Pei Chuan, Wei, Pin Yen, Seppälä, Markku
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Choriocarcinoma - blood
Chorionic Gonadotropin - blood
Female
Glycoproteins
Humans
Hydatidiform Mole - blood
Pregnancy
Pregnancy Proteins - blood
Pregnancy Proteins - metabolism
Pregnancy-Specific beta 1-Glycoproteins - metabolism
Uterine Neoplasms - blood
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Zusammenfassung:Serum levels of human chorionic gonadotropin (hCG), pregnancy-specific beta-1-glycoprotein (SP1), and placental protein 5 (PP5) were measured prior to treatment in 14 patients with hydatidiform mole and in nine patients with choriocarcinoma. Measurement of circulating levels of SP1 and PP5, but not hCG, provides a distinction between benign and malignant gestational trophoblastic tumors.
ISSN:0002-9378
1097-6868
DOI:10.1016/0002-9378(81)90490-7