Treatment with oral estrone sulphate in the female climacteric: I. Influence on lipids

Treatment with oral estrone sulphate in the female climacteric: I. Influence on lipids

Twenty women in the perimenopause were studied for 12 months during which sodium-piperazine-estronesulphate 2.5 mg/day was given for 3 weeks out of 4 as a hormone replacement therapy. Blood samples were drawn at the start of therapy, then after 3, 6 and 12 months and analyzed for serum triglyceride,...

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Veröffentlicht in:Acta obstetricia et gynecologica Scandinavica 1981, Vol.60 (1), p.27-31
Hauptverfasser: Lagrelius, A., Johnson, P., Lunell, N. O., Samsioe, G.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Cholesterol - blood
Climacteric - drug effects
Estrone - analogs & derivatives
Estrone - pharmacology
Fatty Acids - analysis
Female
Humans
Lipids - blood
Lipoproteins - blood
Menopause
Middle Aged
Phosphatidylcholines - analysis
Piperazines - pharmacology
Triglycerides - blood
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Zusammenfassung:Twenty women in the perimenopause were studied for 12 months during which sodium-piperazine-estronesulphate 2.5 mg/day was given for 3 weeks out of 4 as a hormone replacement therapy. Blood samples were drawn at the start of therapy, then after 3, 6 and 12 months and analyzed for serum triglyceride, total cholesterol, cholesterol content of high density lipoprotein (HDL) fraction and the relative fatty acid composition of serum lecithin. Triglyceride levels were increased after 3 months (p
ISSN:0001-6349
1600-0412
DOI:10.3109/00016348109154105