Rapid Quantitative Determination of the Effect of Antiplaque Agents and Antisera on the Growth, Acid Production, and Adherence of Streptococcus mutans

A rapid quantitative in vitro assay measured the effects of antiplaque agents and antiserum on growth and sucrose-mediated adherence of radiolabeled S. mutans 6715. Acid production was measured by change in pH. In this assay the primary effect of chlorhexidine and fluoride was bacteriostasis and inh...

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Veröffentlicht in:	Journal of dental research 1981-03, Vol.60 (3), p.756-762
Hauptverfasser:	Ciardi, J.E., Rosenthal, A.B., Bowen, W.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cariostatic Agents - pharmacology Chlorhexidine - pharmacology Dental Plaque - prevention & control Dentistry Humans Immune Sera - pharmacology Streptococcus mutans - drug effects Streptococcus mutans - growth & development Streptococcus mutans - immunology Streptococcus mutans - metabolism
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Zusammenfassung:	A rapid quantitative in vitro assay measured the effects of antiplaque agents and antiserum on growth and sucrose-mediated adherence of radiolabeled S. mutans 6715. Acid production was measured by change in pH. In this assay the primary effect of chlorhexidine and fluoride was bacteriostasis and inhibition of acid production, respectively; the primary effect of dextran, dextranase, and specific antiserum was inhibition of sucrose-mediated adherence.
ISSN:	0022-0345 1544-0591
DOI:	10.1177/00220345810600031701