Molecular dissection of the myelinated axon

The membrane of the myelinated axon expresses a rich repertoire of physiologically active molecules: (1) Voltagesensitive NA+ channels are clustered at high density (∼1,000/μm2) in the nodal axon membrane and are present at lower density(

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Bibliographische Detailangaben
Veröffentlicht in:	Annals of neurology 1993-02, Vol.33 (2), p.121-136
Hauptverfasser:	Waxman, Stephen G., Ritchie, J. Murdoch
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - ultrastructure Axons - metabolism Biological and medical sciences Calcium-Transporting ATPases - metabolism Carrier Proteins - metabolism Electrophysiology Fundamental and applied biological sciences. Psychology Humans Ion Channels - metabolism Ion Channels - physiology Isolated neuron and nerve. Neuroglia Myelin Sheath - metabolism Nervous System Diseases - drug therapy Neural Conduction Ranvier's Nodes - ultrastructure Schwann Cells - ultrastructure Sodium-Calcium Exchanger Sodium-Potassium-Exchanging ATPase - metabolism Vertebrates: nervous system and sense organs
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Beschreibung
Zusammenfassung:	The membrane of the myelinated axon expresses a rich repertoire of physiologically active molecules: (1) Voltagesensitive NA+ channels are clustered at high density (∼1,000/μm2) in the nodal axon membrane and are present at lower density(
ISSN:	0364-5134 1531-8249
DOI:	10.1002/ana.410330202