Changes in serotonin receptors in different brain regions after light exposure of dark-reared rats

Male rats dark-reared from birth until 50 days of age and then exposed to light for 3 h show significant increases in specific [ 3H]serotonin (5-[ 3H]HT) binding to P 2 membranes from visual and motor cortex and superior colliculus (25, 65 and 23% respectively) as compared with normal and dark-reare...

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Veröffentlicht in:	Neuroscience letters 1980-05, Vol.17 (3), p.317-321
Hauptverfasser:	Murphy, S., Uzbekov, M.G., Rose, S.P.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Dark Adaptation Light Male Motor Cortex - metabolism Muridae Receptors, Serotonin - metabolism Sensory Deprivation - physiology Serotonin - metabolism Space life sciences Superior Colliculi - metabolism Visual Cortex - metabolism Visual Pathways - metabolism Visual Perception - physiology
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Zusammenfassung:	Male rats dark-reared from birth until 50 days of age and then exposed to light for 3 h show significant increases in specific [ 3H]serotonin (5-[ 3H]HT) binding to P 2 membranes from visual and motor cortex and superior colliculus (25, 65 and 23% respectively) as compared with normal and dark-reared littermates. These increases are transient and return to normal levels after 7 days. The role of 5-HT as a transmitter in the visual system is discussed.
ISSN:	0304-3940 1872-7972
DOI:	10.1016/0304-3940(80)90043-9