Correlation between semen analysis by motile sperm organelle morphology examination and sperm DNA damage

Regression analysis of 538 semen samples demonstrated that percentages of normal nuclear sperm and all spermatozoa with abnormalities of nuclear form at high magnification had significant negative correlation with percentages of DNA fragmentation. On the other hand, there was a positive correlation...

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Veröffentlicht in:	Fertility and sterility 2010-10, Vol.94 (5), p.1937-1940
Hauptverfasser:	Oliveira, Joao Batista Alcantara, M.D., Ph.D, Massaro, Fabiana Cagnoto, B.S, Baruffi, Ricardo Luis Razera, M.D, Mauri, Ana Lúcia, B.S, Petersen, Claudia Guilhermino, Ph.D, Silva, Liliane F.I., B.S, Vagnini, Laura D., B.S, Franco, José Gonçalves, M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cell Nucleus - ultrastructure DNA Damage DNA Fragmentation Gynecology. Andrology. Obstetrics Humans Infertility, Male - pathology Infertility, Male - physiopathology Internal Medicine Male Medical sciences Obstetrics and Gynecology Regression Analysis Semen Analysis - methods Sperm Motility - physiology Spermatozoa - physiology Spermatozoa - ultrastructure Vacuoles - ultrastructure
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Beschreibung
Zusammenfassung:	Regression analysis of 538 semen samples demonstrated that percentages of normal nuclear sperm and all spermatozoa with abnormalities of nuclear form at high magnification had significant negative correlation with percentages of DNA fragmentation. On the other hand, there was a positive correlation between percentages of spermatozoa with nuclear vacuoles and those with DNA fragmentation.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2010.01.042