Tocopherol acetate reference standard (Control 911) of the National Institute of Hygienic Sciences

Tocopherol acetate reference standard (Control 911) of the National Institute of Hygienic Sciences

The raw material for tocopherol acetate was tested for preparation of the "Tocopherol Acetate Reference Standard (Control 911)". Analytical data obtained were as follows: infrared spectrum, same as Tocopherol Acetate Reference Standard (Control 881); absorptivity, E1cm1% (284nm) = 43.5; th...

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Veröffentlicht in:Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 1992 (110), p.119-121
Hauptverfasser: Izumi, W, Murai, M, Komatsu, H, Ishimitsu, S, Okada, S
Format: Artikel
Sprache:jpn
Schlagworte:
Chromatography, High Pressure Liquid
Government Agencies
Hygiene
Japan
Pharmacopoeias as Topic
Spectrophotometry, Infrared
Vitamin E - isolation & purification
Vitamin E - standards
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Zusammenfassung:The raw material for tocopherol acetate was tested for preparation of the "Tocopherol Acetate Reference Standard (Control 911)". Analytical data obtained were as follows: infrared spectrum, same as Tocopherol Acetate Reference Standard (Control 881); absorptivity, E1cm1% (284nm) = 43.5; thin-layer chromatography, no impurities were detected up to 50.0 micrograms; high performance liquid chromatography (HPLC), two impurities were detected; assay, 100.3% by HPLC. Based on the above results, the raw material was authorized as the Japanese Pharmacopoeia Standard (Control 911).
ISSN:0077-4715