Mouse liver and salivary gland α -amylase mRNAs differ only in 5′ non-translated sequences

The sequence of the 1,773-nucleotide major and 1,806-nucleotide minor mouse liver α-amylase mRNAs differ only with respect to approximately 30 additional residues at the extreme 5′ terminus of the minor species. Comparison of the liver α-amylase mRNAs with their salivary gland counterpart reveals th...

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Veröffentlicht in:Nature (London) 1981-02, Vol.289 (5799), p.643-646
Hauptverfasser: Hagenbüchle, Otto, Tosi, Mario, Schibler, Ueli, Bovey, Raymonde, Wellauer, Peter K, Young, Richard A
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Sprache:eng
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Zusammenfassung:The sequence of the 1,773-nucleotide major and 1,806-nucleotide minor mouse liver α-amylase mRNAs differ only with respect to approximately 30 additional residues at the extreme 5′ terminus of the minor species. Comparison of the liver α-amylase mRNAs with their salivary gland counterpart reveals that these mRNAs share identical coding and 3′-noncoding sequences, but contain distinct 5′-terminal residues. These data suggest that all three mRNAs might be transcribed from the same gene.
ISSN:0028-0836
1476-4687
DOI:10.1038/289643a0