Differential health benefits of weight loss in upper-body and lower-body obese women

Upper-body obesity (UB Ob) is more strongly associated with adverse health consequences; however, few obesity-treatment studies have examined outcome according to body-fat distribution. To examine whether diet and formal- or informal-exercise instruction causes differential changes in health and lip...

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Veröffentlicht in:The American journal of clinical nutrition 1993-01, Vol.57 (1), p.20-26
Hauptverfasser: Kanaley, JA, Andresen-Reid, ML, Oenning, L, Kottke, BA, Jensen, MD
Format: Artikel
Sprache:eng
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Zusammenfassung:Upper-body obesity (UB Ob) is more strongly associated with adverse health consequences; however, few obesity-treatment studies have examined outcome according to body-fat distribution. To examine whether diet and formal- or informal-exercise instruction causes differential changes in health and lipid profiles, ten LB Ob and nine UB Ob premenopausal women received dietary intervention (2.1 MJ-deficit/d for 16 wk) and were randomly assigned to either formal- or informal-exercise instruction. Weight loss was similar between groups (≈8 kg), and no change occurred in lean body mass or basal metabolic rate. Baseline cholesterol and triglycerides were greater (P < 0.01 ) in UB Ob than LB Ob women and decreased more (P < 0.01) in response to treatment in UB Ob women. Formal exercise instruction increased high-density-lipoprotein cholesterol (P < 0.05) especially in UB Ob women. Future studies on treatment of obesity should include consideration of regional fat distribution.
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/57.1.20