Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch

A thermosensitive liposome with embedded AuNPs in a bilayer was prepared using supercritical CO(2). The AuNPs-liposome can absorb a certain wavelength light, convert optical energy into heat, induce phase transition, and release drug. The results show that drug release from the liposome is due to th...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2010-10, Vol.46 (38), p.7202-7204
Hauptverfasser: An, Xueqin, Zhang, Fan, Zhu, Yinyan, Shen, Weiguo
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creator An, Xueqin
Zhang, Fan
Zhu, Yinyan
Shen, Weiguo
description A thermosensitive liposome with embedded AuNPs in a bilayer was prepared using supercritical CO(2). The AuNPs-liposome can absorb a certain wavelength light, convert optical energy into heat, induce phase transition, and release drug. The results show that drug release from the liposome is due to the photothermic effects inducing phase transition of the liposome rather than destruction of the liposome structure.
doi_str_mv 10.1039/c0cc03142a
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Berberine - administration & dosage
Delayed-Action Preparations - chemistry
Gold - chemistry
Hot Temperature
Liposomes - chemistry
Liposomes - ultrastructure
Nanoparticles - chemistry
Nanoparticles - ultrastructure
Pharmaceutical Preparations - administration & dosage
Phase Transition
Photochemical Processes
Ultraviolet Rays
title Photoinduced drug release from thermosensitive AuNPs-liposome using a AuNPs-switch
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